Cromossoma 10

Par de cromossoma 10

O cromossoma 10 é um dos 23 pares de cromossomas do cariótipo humano.

Genes

• ALOX5: Arachidonate 5-Lipoxygenase (processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response; also facilitates development and maintenance of cancer stem cells, slow-dividing cells thought to give rise to a variety of cancers, including leukemia);

Gene	Descrição
CDH23	cadherin-like 23
CXCL12	chemokine (C-X-C motif) ligand 12, SDF-1, scyb12
EGR2	early growth response 2 (Krox-20 homolog, Drosophila)
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6
FGFR2	fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
HELLS	Lymphoid-specific helicase
PCBD1	6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
PCDH15	protocadherin 15
PTEN gene	phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
RET	ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
UROS	uroporphyrinogen III synthase (congenital erythropoietic porphyria)

Doenças

O cromossomos é constituído por 24 genes colaterais